Genome Wide Association SNP Genotyping

InforSense GenSense provides a complete and flexible solution that enables the analysis of data from the latest generation of high-throughput genotyping platforms.

It has been specifically designed to assist researchers using genotyping arrays by providing the following capabilities.

• Work with large volume data sets, including chips that measure up to one million SNP's across 1000's of samples
• Support for Affymetrix and Illumina data formats
• Automated quality control to filter SNP's and samples based on genotype quality score, genotype completion and sample duplication
• Statistical analysis of case control data and view the results with appropriate visualizations
• Filter, sort and prioritize SNPs
• Prebuilt, flexible connectors for 3rd party tools and scripts (e.g. R and Perl)
• Link to phenotype data to find those SNPs most highly associated with disease and/or drug response.

InforSense GenSense also enables SNPs of interest to be further characterized and interpreted using the genome annotation tools in InforSense BioSense. The Genome Wide studies data can be integrated with sequence analysis workflows to further investigate the genes associated with disease relevant SNPs. The results may also be analyzed with InforSense TextSense to collect and prioritize the most appropriate scientific articles. For complex phenotypic information InforSense ClinicalSense gives the user the ability to design experiments and answer complex questions involving sample stratification.